For the Animals
An Argument Guide
PT

Home / I. Other uses: testing, clothing, entertainment / Part IND

I1

"Animal testing has saved millions of lives."

The answer in one sentence

benefit doesn't justify using those who can't consent. Testing on children or on people unable to consent would also bring benefits, and no one accepts it. Besides, about 90% of drugs that pass preclinical testing fail in human trials, partly because animals aren't good models of human disease. In 2022 the United States stopped requiring animal testing for new drugs, opening the way for alternative methods.

Short answer

That testing brought benefits isn't enough: testing on people who can't consent would too, and no one accepts it. Besides, about 90% of drugs that pass preclinical testing fail in humans, partly because animals don't reproduce human diseases well. In 2022, the United States stopped requiring animal tests for new drugs, allowing alternative methods.

For children

Scientists have used many animals to test medicines. Some tests helped discover important things. But the animals didn't choose to take part, and many suffered. Today there are new ways to test medicines without using animals, such as cells in a lab and computers, and lots of people are working to have them replace animal tests.

Ask a question back

"If benefit justifies using those who don't consent, why don't we test on humans who can't consent?"

Como pode aparecer

"Would you rather test on children?"
Everyday conversation
"Without rats there'd be no vaccines."
Everyday conversation
"Medicine needs it."
Everyday conversation
"Want a cure for cancer without animal testing?"
Social media
"Preclinical research on animals is indispensable."
Technical version
"If you take medicine, you can't oppose testing." (which is I2)
Disguised version

The strongest version

How it is said

"Would you rather test on children? Without rats there'd be no vaccines. Medicine needs it."

Strongest version (steelman):

  1. P1Research on animals has contributed to many medical advances, such as vaccines and treatments.
  2. P2Those advances have saved millions of human lives.
  3. P3Saving human lives justifies causing animals some suffering.
  4. CSo animal testing is justified.

P1 and P2 are true. The problem lies in P3: benefit to some doesn't, by itself, justify using others without consent, and the usefulness of the tests is smaller than people tend to think.

The argument is valid. Its soundness fails at P3, and P1 is weaker than it looks.

Full answer

  1. a

    Reconstruction and diagnosis

    The argument depends on two ideas:

    IdeaStatus
    Animal tests have brought benefitsPartly true
    Benefit justifies using those who don't consentAccepted in no other case
    Animal tests are indispensable todayDisputed: high failure rate and growing alternative methods
  2. b

    Where the argument breaks

    1. Benefit doesn't justify using those who don't consent.

    Testing on humans without consent would also bring benefits, and it was banned after historical abuses. The criterion that protects vulnerable humans should apply to other sentient beings.

    2. The failure rate is high.

    According to a 2022 analysis, about 90% of drug candidates that enter clinical trials fail. Among the reasons cited is the biological difference between animal models and humans. The figure doesn't prove animal tests are useless, since failures have many causes; it shows they are far from guaranteeing safety and efficacy, which weakens the idea that they're indispensable.

    3. There are alternative methods.

    Organoids, organs-on-chips, human cell cultures and computer models are being developed and validated.

    4. The law is changing.

    The FDA Modernization Act 2.0, of 2022, removed the requirement for animal testing of new drugs in the United States, allowing non-animal methods. In the European Union, the directive on animals used in science (2010/63/EU) already sets full replacement as its ultimate goal.

    5. The argument says nothing about eating animals.

    Even if testing were justified, that wouldn't justify meat, milk and eggs.

  3. c

    Data and sources

    SourceWhat it saysNote
    Sun et al., 2022, *Acta Pharmaceutica Sinica B*About 90% of drug candidates entering clinical trials fail; the discrepancy between animal models and humans makes validation harderAn analysis of drug development
    Connecticut Public, on the FDA Modernization Act 2.0Since late 2022, the FDA no longer requires all drugs to be tested on animals before human trialsNews report; the law doesn't ban testing, but allows alternatives
  4. d

    The strongest counter-reply: there aren't alternatives for everything yet

    The most serious version grants the problems, but says there aren't yet alternatives for every type of test, and that abandoning testing all at once would delay life-saving treatments.

  5. e

    Why the counter-reply doesn't reach the conclusion

    That justifies investing in alternatives.

    If tests are still used, the priority should be replacing them.

    It doesn't justify unnecessary tests.

    Many tests are done because of bureaucratic requirements, not scientific necessity.

    The dilemma doesn't apply to food.

    Eating animals doesn't save human lives.

  6. f

    Back to the moral question

    Testing is one of the hardest cases, because it involves human lives. But even here the moral question doesn't disappear: is it acceptable to use those who don't consent for the benefit of others? For food, where no human lives are at stake, the answer is even clearer.

Reasoning errors

Logical

Is the form valid?

False dilemma
Either animal testing or testing on children

Epistemological

Does the evidence support it?

Overestimating effectiveness
Ignores the high translational failure rate

Moral

Is the criterion coherent?

Selective consequentialism
Applies the cost-benefit calculation only to animals

Biases

Speciesism

Consent only matters for humans

Caviola, Everett and Faber, 2019

Status quo bias

The current research system seems the only one possible

Samuelson and Zeckhauser, 1988

Extrapolations

The principle being tested is: "if using someone benefits many, it's justified".

If it applied to…Testing on people without consentTap to see

It would be justified

Banned after historical abuses

If it applied to…Forced organ removalTap to see

It would be justified to save several lives

No one accepts this

If it applied to…PetsTap to see

They could be used in tests

Many people object

Contradictions

Doesn't accept testing on humans without consent.

Even if it brought benefits.

Uses the argument to justify meat.

Which doesn't save lives.

Supports alternatives in other areas.

Such as cosmetics not tested on animals.

What the argument gets right

What is true

Animal testing has contributed to real medical advances, and many people are alive because of treatments developed with it. It's also true that there aren't yet alternatives for every type of test, and that the transition requires investment and care.

But

But the benefit doesn't erase the cost to those who didn't consent. Science is developing alternatives, and the law is beginning to follow. And above all, none of this justifies eating animals.

Connections

Usually comes before

I1this argument

Usually comes after

Go deeper in Questão de Ética

Chapters from the open-access collection A Journey Through Animal Ethics that discuss this argument in more detail:

References